The diagnostic algorithms within Cardea 20/20 ECG™ are built on the recent research of the company founders and other notable colleagues, particularly those at Stanford University and the University of Washington. These efforts have recently culminated in the publication of the International Consensus for ECG Interpretation in Athletes—formerly the Seattle Criteria. (see British Journal of Sports Medicine).

The following research papers, co-authored by the company founders, provide the background foundations leading to the development of Cardea 20/20 ECG.

QT Corrections for Long QT Risk Assessment: Implications for the Pre-participation Examination. Hadley, David PhD; Hsu, David BS; Pickham, David PhD; Drezner, Jonathan A. MD; Froelicher, Victor F. MD

Cost-effectiveness of pre-participation screening for prevention of sudden cardiac death in young athletes.”

A novel method for patient-specific QTc–modeling QT-RR hysteresis.”

The impact of ST elevation on athletic screening.”

Interpretation of the electrocardiogram of young athletes.”

Early repolarization in an ambulatory clinical population.”

Natural history of the electrocardiographic pattern of early repolarization in ambulatory patients.”

Addition of the electrocardiogram to the preparticipation examination of college athletes.”

T-wave abnormalities are a better predictor of cardiovascular mortality than ST depression on the resting electrocardiogram.”

Prognostic importance of isolated T-wave abnormalities.”

Prognostic value of electrocardiographic criteria for left ventricular hypertrophy.”

Prognostic Significance of Quantitative QRS Duration.”

Prognostic significance of PVCs and resting heart rate.”

Electrocardiographic arrhythmia risk testing.”

The Prognostic Value of T Wave Amplitude in Lead aVR in Males.”

The prevalence and prognostic significance of electrocardiographic abnormalities.”

An evidence-based review of the resting electrocardiogram as a screening technique for heart disease.”

Semantic Confusion: The Case of Early Repolarization and the J Point.”

The prognostic importance of isolated P-Wave abnormalities.”

Effect of gender on computerized electrocardiogram measurements in college athletes.”

The Effect of Sport on Computerized Electrocardiogram Measurements in College Athletes.”

The Seattle Criteria:

Electrocardiographic interpretation in athletes: the ‘Seattle Criteria’.”

Normal electrocardiographic findings: recognizing physiological adaptations in athletes.”

Abnormal electrocardiographic findings in athletes: recognising changes suggestive of cardiomyopathy. ”

Abnormal electrocardiographic findings in athletes: recognising changes suggestive of primary electrical disease. ”